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This season, we've curated a vibrant collection inspired by blooming coastal landscapes, breezy beach days, and the joyful spirit of springtime by the sea Remitting seronegative symmetrical synovitis with pitting oedema (RS3PE) syndrome is a rare disease that typically presents in older men and is characterised by bilateral and symmetrical peripheral arthritis, pitting oedema in the dorsal hands and feet, and seronegativity for rheumatoid factor Prognosis is reported to be good, although many patients are still requiring low-dose oral steroids and/or disease-modifying anti- rheumatic drugs such as methotrexate a year or more after diagnosis.
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Pleasure Beach NEW RIDE FOR 2023 HUGE NEWS, Updates, + More! Blackpool Pleasure Beach. Remitting seronegative symmetrical synovitis with pitting edema (or sometimes RS 3 PE) is a rare syndrome identified by symmetric polyarthritis, synovitis, acute pitting edema (swelling) of the back of the hands and/or feet, and a negative serum rheumatoid factor However, several other features point to a possible role of autoinflammation in RS3PE syndrome.